Attorney General William Barr and Interior Secretary David Bernhardt will oversee the effort, which targets new and unsolved missing person and murder cases.
Donald Trump signed an executive order Tuesday creating a White House task force on missing and slain American Indians and Alaska Natives.
The task force will be overseen by Attorney General William Barr and Interior Secretary David Bernhardt. It will develop protocols to apply to new and unsolved case and create a multi-jurisdictional team to review cold cases.
Trump called the scourge facing American Indian women and girls "sobering and heartbreaking."
"We will leverage every resource we have to bring safety to our tribal communities, and we will not waver in this mission," Trump said. "We're taking this very seriously."
Trump's announcement comes days after Barr said the Justice Department would invest $1.5 million to hire specialized coordinators in 11 U.S. attorney's offices with significant caseloads from Indian Country to come up with ways to better respond to missing persons cases and committed FBI resources. Barr said the agency also would do an in-depth analysis of federal databases and its own data collection process.
The National Institute of Justice estimates that 1.5 million American Indian women have experienced violence in their lifetime, including many who are victims of sexual violence. On some reservations, federal studies have shown women are killed at a rate over 10 times the national average.
The executive order also directs the Justice Department to make grant funding available to improve public safety in tribal communities.
Trump was joined by representatives of the Navajo Nation, which extends into New Mexico, Arizona, and Utah; the Crow Nation in Montana; and the Mille Lacs Band of Ojibwe and the Fond du Lac Band of Lake Superior Chippewa in Minnesota.
Fond du Lac Chairman Kevin DuPuis highlighted women as caretakers of children and tribal villages and said it's imperative that they be protected and not treated as second-class citizens.
"It's very, very important that we, as a people, have a true identity," he said. "And when we lose our women and we lose our children, that goes with them."
The Seattle Indian Health Board urged the Trump administration to keep in mind that a majority of American Indians live off reservations.
"This action is a step in the right direction, but we look forward to seeing additional steps that are inclusive of urban Indian people," the board's chief research officer, Abigail Echo-Hawk, said in a statement.
The task force expires after two years. It is expected to report on its work in a year.